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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BROX
All Species:
22.12
Human Site:
S362
Identified Species:
44.24
UniProt:
Q5VW32
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VW32
NP_653296.2
411
46476
S362
P
F
E
F
P
P
T
S
V
Q
W
T
P
E
T
Chimpanzee
Pan troglodytes
XP_001173118
411
46488
S362
P
F
E
F
P
P
T
S
V
Q
W
T
P
E
T
Rhesus Macaque
Macaca mulatta
XP_001099998
411
46403
S362
P
F
E
F
P
P
T
S
A
Q
W
T
P
E
T
Dog
Lupus familis
XP_536151
461
51635
S412
P
F
E
F
P
P
T
S
A
Y
W
T
P
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Q7
411
46183
S362
P
F
E
F
P
P
M
S
A
H
W
T
P
E
A
Rat
Rattus norvegicus
Q4V8K5
411
46173
S362
P
F
E
F
P
P
M
S
A
L
W
T
P
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512145
469
53140
N420
P
F
E
F
P
P
V
N
A
H
W
T
P
E
T
Chicken
Gallus gallus
XP_419397
411
46534
N362
P
F
E
F
P
A
L
N
A
H
W
T
P
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KQV2
411
46106
S362
A
F
E
L
P
P
L
S
A
Q
C
T
P
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120754
420
47151
N371
D
F
Q
M
Q
S
H
N
S
I
W
N
L
N
V
Nematode Worm
Caenorhab. elegans
Q22885
427
48281
A372
S
F
T
Y
P
P
P
A
E
S
W
N
T
A
V
Sea Urchin
Strong. purpuratus
XP_784283
330
36694
G288
F
E
K
A
D
E
L
G
R
S
Y
T
A
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.2
84.8
N.A.
91.7
92.4
N.A.
78.4
86.3
N.A.
74.2
N.A.
N.A.
45
39.5
34.7
Protein Similarity:
100
99.7
99.5
87.1
N.A.
96.8
96.8
N.A.
82.7
92.9
N.A.
86.3
N.A.
N.A.
60
60.8
50.8
P-Site Identity:
100
100
93.3
80
N.A.
73.3
73.3
N.A.
73.3
66.6
N.A.
60
N.A.
N.A.
13.3
26.6
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
73.3
73.3
N.A.
80
73.3
N.A.
60
N.A.
N.A.
26.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
9
0
9
59
0
0
0
9
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
9
75
0
0
9
0
0
9
0
0
0
0
67
0
% E
% Phe:
9
92
0
67
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
25
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
9
0
0
25
0
0
9
0
0
9
0
0
% L
% Met:
0
0
0
9
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
25
0
0
0
17
0
9
0
% N
% Pro:
67
0
0
0
84
75
9
0
0
0
0
0
75
0
0
% P
% Gln:
0
0
9
0
9
0
0
0
0
34
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
0
9
0
59
9
17
0
0
0
0
0
% S
% Thr:
0
0
9
0
0
0
34
0
0
0
0
84
9
9
50
% T
% Val:
0
0
0
0
0
0
9
0
17
0
0
0
0
0
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
84
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _